Tobias Koslowski lost the ability to play music five years ago, due to muscular dystrophy, but today he’s writing and performing saxophone with the help of the Jamboxx, a breath-driven musical instrument. The device and accompanying software allows novices and professional musicians alike to play 200-plus sounds — from electric guitar to oboe — right out of the box.

“I was missing the ability to play melodies and arrange music,” says Koslowski, 36. Now he writes his own “chill out” songs in a style similar to Café del Mar. “I am making music,” says the resident of Dusseldorf, Germany. “It really works.”

The Jamboxx is the brainchild of David Whalen, another musician who lived his first 25 years post-injury without the ability to jam with frien